Microcirculatory Flux and Pulsatility in Arterial Leg Ulcers is Increased by Intermittent Neuromuscular Electrostimulation of the Common Peroneal Nerve

BackgroundNeuromuscular electrical stimulator (NMES) devices increase blood flow to the lower limb by a process of intermittent muscular contraction initiated transdermal stimulus common peroneal nerve. However, its effects on localized microvascular supply wounds are unknown. This study is single-center open label measuring effect neuromuscular stimulation nerve within wound bed arterial leg ulcers.MethodsEights patients with ischemic had an NMES (geko™) applied Baseline and intervention analysis edge was performed using Laser Speckle Contrast Imaging. Mean (flux) pulse amplitude (pulsatility) were measured.ResultsStimulation resulted in significantly increased flux pulsatility both all 8 patients.ConclusionsNeuromuscular immediately increases microcirculatory wounds. These data may provide mechanistic insight into clinical efficacy healing wounds.www.clinicaltrials.gov NCT03186560. Neuromuscular ulcers. Eights measured. Stimulation patients.